Economic and healthcare influences on circulatory diseases in Kazakhstan: a retrospective ecological study.

Background: Health is a key driver of the United Nations Sustainable Development Goals. This study examined the relationships between economic indicators, demographic metrics, and health system factors and morbidity due to non-communicable diseases, such as diseases of the circulatory system, in Kazakhstan.

Methods: This retrospective ecological study utilized regionally aggregated data from 2010 to 2020 for all 14 regions in Kazakhstan.

Cysteine Prevents the Development of Experimental Diabetes Induced by Zinc-Binding Substances.

In experimental rabbits, cysteine injected intravenously in a dose of 1000 mg/kg temporarily bound zinc in β cells and prevented the formation of chelate zinc complexes in response to subsequent injection of diabetogenic zinc-binding substances that induce cell destruction. Injection of cysteine to animals was associated with a sharply negative reaction to zinc in β cells, which attests to blockade of zinc ions. Injection of cysteine few minutes after dithizone and formation of zinc-dithizone complex was followed by displacement of dithizone from the complex and prevented the development of diabetes in most animals.