[Tumor markers MCA and CA-125 in the diagnosis and monitoring of breast cancer].

The value of MCA and CA-25 tumor marker assays for diagnosis and treatment of breast cancer was analysed on the basis of measurements made in 320 healthy females and 85 breast cancer patients. A procedure for DK assay with anticipated specificity, sensitivity and reliability is described. MCA measurement was shown to be important for breast cancer diagnosis.

[A method of modified neuroleptanalgesia in lung surgery].

A modification of neuroleptanalgesia (NLA) has been developed to be applied in operations on the lungs. It is based on the inclusion of indomethacin and diazepam into premedication, on the bolus administration of phentanyl, droperidol, and diazepam prior to the most traumatic stages of the operation, and on the subsequent infusion of phentanyl and droperidol. The modified technique of NLA has been applied in operations on 19 patients with lung cancer.

[The effect of normobaric hypoxia on the functioning of links in the endocrine system].

The paper is concerned with the data on change in the blood level of ACTH, STH, TSH, cortisol, T3, insulin, C-peptide during a 25-minute session of respiration using a gaseous hypoxic mixture with 10% oxygen (GHM-10). The investigation was performed in 23 healthy volunteers. Change in the hormonal status, characteristic of a moderate stress-reaction, was observed in 60% of the examinees.