[AntI-inflammatory, antipyretic and antimicrobial activity of flavonoid-containing extract of Gratiola officinalis L].

The extract of Gratiola officinalis L. has been obtained by an original method ensuring the maximum yield of flavonoids. The extract simultaneously exhibits high anti-inflammatory activity, selective antimicrobial properties (with respect to Staphylococcus aureus and Pseudomonas aeruginosa, but not to conditionally pathogenic E.

[Influence of electromagnetic emission at the frequencies of molecular absorption and emission spectra of oxygen and nitrogen oxide on the adhesion and formation of Pseudomonas aeruginosa biofilm].

Aim: Evaluate the influence of electromagnetic emission (EME) at the frequencies of molecular absorption and emission spectra of atmospheric oxygen and nitrogen oxide (MAES 02 and MAES NO respectively) on the adhesion, population progress and biofilm formation of Pseudomonas aeruginosa.

Materials And Methods: Adhesive activity was evaluated by mean adhesion index (MAI) of bacteria on human erythrocytes. Population growth dynamic was assessed by optical density index of broth cultures; biofilm formation--by values of optical density of the cells attached to the surface of polystyrol wells.

[Circulation of methicillin-resistant staphylococci in hospitals with different profiles].

Analysis of prevalence of methicillin-resistant staphylococci in hospitals with different specializations was performed. 2584 strains were isolated. Methicillin-resistant (MR) strains were present in different profile hospitals and their total prevalence between isolated strains was 12.

[Chemotherapeutic effect of 3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole in experimental staphylococcal infection].

Chemotherapeutic activity of 3-(5-nitrofuryl)-7-(5-nitrofurfuryliden)-3, 3a, 4, 5, 6, 7-hexahydro-2H-indazol (compound 26) was studied on albino mice with experimental staphylococcal infection. The animals were contaminated intraperitoneally. The results of culture of the specimens of the organs of the mice killed within various terms and the values of the spleen bacterial index served as the criteria of the effectiveness.

[Donor activity of methicillin resistant staphylococci in transduction experiments].

Antibiotic resistance gene transmission from methicillin resistant strains of Staphylococcus aureus (MRSA), isolated in a burn care unit, was studied in transduction experiments with type phages 29, 52, 52A and in experiments with prophage induction. The results of the experiments demonstrated high donor activity of MRSA. Recombinants with different antibiotic resistance phenotypes were revealed, but there were no methicillin resistant staphylococci among them.