Publications by authors named "G M Saperia"

Takotsubo cardiomyopathy is a form of reversible left ventricular dysfunction that is presumably precipitated by stress. Our observations of the recurrence of takotsubo cardiomyopathy in an individual and the occurrence of a reversible cardiomyopathy in her daughter lead us to speculate on the possibility of a familial predisposition to this entity or its variants.

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Takotsubo cardiomyopathy is a recently recognized form of transient left ventricular dysfunction that is presumably precipitated by stress and may clinically resemble an acute coronary syndrome. These patients have an akinetic left ventricular apex in an unusual shape that resembles a takotsubo. Although reports of single episodes of takotsubo cardiomyopathy are not infrequent in recent medical literature, we report a case of recurrence that may provide more insight into the nature of this syndrome.

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Background: Although primary care physicians understand the importance of preventive services for patients with multiple risk factors (MRF) for coronary heart disease, physician intervention is limited. This study investigated (1) physicians' views of challenges faced in managing patients with MRF; (2) the counseling and management methods they utilize; and (3) possible strategies to enhance MRF intervention in the primary care setting.

Methods: Two focus groups were conducted with primary care physicians from varying settings to gain insight into these issues noted above.

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Background: A variety of studies have noted seasonal variation in blood lipid levels. Although the mechanism for this phenomenon is not clear, such variation could result in larger numbers of people being diagnosed as having hypercholesterolemia during the winter.

Methods: We conducted a longitudinal study of seasonal variation in lipid levels in 517 healthy volunteers from a health maintenance organization serving central Massachusetts.

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