Publications by authors named "G M Santorelli"

Background: Observational studies suggested chronotype was associated with pregnancy and perinatal outcomes. Whether these associations are causal is unclear. Our aims are to use Mendelian randomization (MR) to explore (1) associations of evening preference with stillbirth, miscarriage, gestational diabetes, hypertensive disorders of pregnancy, perinatal depression, preterm birth and offspring birthweight; and (2) differences in associations of insomnia and sleep duration with those outcomes between chronotype preferences.

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Article Synopsis
  • - Children born via cesarean delivery have a greater risk of various health issues compared to those born vaginally, but the exact reasons are still not fully understood.
  • - A meta-analysis involving over 12,000 participants found six specific DNA methylation markers in newborns linked to cesarean delivery, but these markers did not persist into childhood.
  • - The study indicates that cesarean delivery affects certain blood cell proportions at birth, but further research is necessary to understand its long-term impacts on child health.
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Objective: To explore associations between maternal body mass index (BMI) in early pregnancy and childhood infections.

Design: Birth cohort study linked to primary care records.

Setting: Bradford, UK.

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Background: Lower socioeconomic position (SEP) associates with adverse pregnancy and perinatal outcomes and with less favourable metabolic profile in nonpregnant adults. Socioeconomic differences in pregnancy metabolic profile are unknown. We investigated association between a composite measure of SEP and pregnancy metabolic profile in White European (WE) and South Asian (SA) women.

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