Publications by authors named "G M Sacha"
Article Synopsis
- The study investigates the effectiveness of two weight-based dosing strategies for atracurium in obese patients with acute respiratory distress syndrome (ARDS) during the COVID pandemic, focusing on oxygenation changes after treatment.
- It compares the outcomes of patients receiving atracurium based on actual body weight (ABW) versus ideal body weight (IBW), finding no significant difference in oxygenation improvement after 48 hours despite different dosing amounts.
- The results indicated higher atracurium doses in the ABW group, but no differences in mortality rates or days free from ICU or ventilator support, suggesting both dosing methods may be equally viable for this patient population.
Article Synopsis
- Prompt treatment of sepsis and septic shock is crucial to reducing mortality risk, and tools like alerts and rapid response teams are often used to speed up care, though their effectiveness is not well understood.
- A study assessed an Inpatient Code Sepsis protocol at a hospital over three years to determine its impact on 30-day mortality and other outcomes in patients with sepsis.
- The findings showed no significant change in mortality rates after implementing the protocol, but there was a notable decrease in the time it took to administer antibiotics.
Objective: Conventional prediction models fail to integrate the constantly evolving nature of critical illness. Alternative modelling approaches to study dynamic changes in critical illness progression are needed. We compare static risk prediction models to dynamic probabilistic models in early critical illness.
View Article and Find Full Text PDFReduction in sedation exposure is an important metric in intensive care unit (ICU) patients. However, challenges arose during the coronavirus disease-2019 (COVID-19) pandemic in adhering to this practice, driven by concerns on transmission and disease severity issues. Accordingly, diverse sedation approaches emerged, although the effect on mortality has not been studied thoroughly.
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