Publications by authors named "G M Maher"
To identify novel genes responsible for recurrent hydatidiform moles (HMs), we performed exome sequencing on 75 unrelated patients who were negative for mutations in the known genes. We identified biallelic deleterious variants in 6 genes, FOXL2, MAJIN, KASH5, SYCP2, MEIOB, and HFM1, in patients with androgenetic HMs, including a familial case of 3 affected members. Five of these genes are essential for meiosis I, and their deficiencies lead to premature ovarian insufficiency.
View Article and Find Full Text PDFObjectives: Development and validation of risk prediction models at mid-pregnancy and delivery to predict admission to the neonatal care unit.
Methods: We used data from all singleton deliveries at Cork University Maternity Hospital (CUMH), Ireland during 2019. Admission to the neonatal care unit was assumed if length of stay in the unit was > 24 h.
Article Synopsis
- Landslides are a rare but dangerous issue in Egypt, particularly on the El Mokattam plateau in Cairo, where the study focuses on identifying and monitoring them.
- The research uses various geophysical methods, including Electrical resistivity tomography, P-wave seismic refraction, and high-frequency microtremor analysis, to understand the causes of landslides in the area.
- Key factors such as steep slopes, fractured rocks, and irrigation water were found to contribute to landslides, with microtremor analysis showing potential correlations that could help pinpoint landslide-prone zones.
Background: Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the assessment and refinement of innovative prototype preeclampsia risk assessment tests based on emerging biomarker technologies. Here we describe IMPROvED's profile and invite researchers to collaborate.
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