Treatment of early-stage diabetic nephropathy with Siddha drug Sirupeelai Kudineer: A case series.

Diabetic Nephropathy is one of the major microvascular complications of Diabetes Mellitus, which can be detected in the earlier stage by investigating urinary microalbumin excretion levels and estimating ACR and GFR. Early treatment can delay or prevent the progression of diabetic Nephropathy. Monoherbal Siddha formulation Sirupeelai Kudineer indicated for the complications of Diabetes Mellitus is selected for this Case study.

Luminescent carbon dots quantum dots and gold nanoclusters as sensors.

Ultra-small nanoparticles, including quantum dots, gold nanoclusters (AuNCs) and carbon dots (CDs), have emerged as a promising class of fluorescent material because of their molecular-like properties and widespread applications in sensing and imaging. However, the fluorescence properties of ultra-small gold nanoparticles (, AuNCs) and CDs are more complicated and well distinguished from conventional quantum dots or organic dye molecules. At this frontier, we highlight recent developments in the fundamental understanding of the fluorescence emission mechanism of these ultra-small nanoparticles.

Folic acid incorporated nitrogen-doped carbon dots as a turn-on fluorescence probe for homocysteine detection.

This study describes the development of a low-cost fluorescence assay for detecting homocysteine (Hcy) without the interference of cysteine and glutathione using carbon quantum dots. Herein nitrogen-doped carbon quantum dots (NCDs) were synthesized from citric acid as the carbon source and urea as the dopant using a one-pot microwave-assisted method. The obtained NCDs were incorporated with folic acid (FA) by the direct ex situ addition method and were used as a fluorescence probe to detect Hcy.

Dopamine-induced photoluminescence quenching of bovine serum albumin-capped manganese-doped zinc sulphide quantum dots.

The direct detection of dopamine (DA) in human body fluids is a great challenge for medical diagnostics of neurological disorders like Parkinson's disease, Alzheimer's disease, senile dementia, and schizophrenia. In this work, a simple and turn off luminescence sensing of DA based on bovine serum albumin (BSA)-capped manganese-doped zinc sulphide quantum dots (Mn:ZnS/BSA QDs) is developed. The Mn:ZnS/BSA QDs were synthesized by a chemical co-precipitation method.