Equivalence of Biosimilarity in Pharmacokinetic and Pharmacodynamic Properties of Recombinant Human Insulin Aspart.

Insulin aspart, a rapid-acting analog, achieves faster subcutaneous absorption than regular insulin. This study aimed to demonstrate equivalence in the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of Recombinant Human Insulin Aspart from BioGenomics Limited (as test) and Novo-Nordisk (as reference) in healthy adult males. This was a double-blind, randomized, cross-over study, assessing PK and PD parameters under fasting conditions.

An comparison of the fracture resistance of MOD inlay restorations using different lithium disilicates.

Objective: The objective of this study was to evaluate and compare the fracture resistance of MOD inlay preparations restored with two different lithium disilicate glass ceramics.

Materials And Methods: Standardized MOD inlay cavities were prepared on 64 human permanent premolar teeth and divided into two groups to be restored with lithium disilicate glass-ceramic materials, i.e.

A Self-Formed Ag Nanostructure Based Neuromorphic Device Performing Arithmetic Computation and Area Integration: Influence of Presynaptic Pulsing Scheme on Mathematical Precision.

A material equivalent of a biosynapse is the key to neuromorphic architecture. Here we report a self-forming labyrinthine Ag nanostructure activated with a few pulses of 0.5 V, width and interval set at 50 ms, at current compliance () of 400 nA, serving as the active material for a highly stable device with programmable volatility.