Publications by authors named "G M Garcia-Garcia"
Local hyperthermia is gaining considerable interest due to its promising antitumor effects. In this context, dual magneto-photothermal cancer therapy holds great promise. For this purpose, the use of nanomaterials has been proposed.
View Article and Find Full Text PDFThe AGBL5 gene encodes for the Cytoplasmic Carboxypeptidase 5 (CCP5), an α-tubulin deglutamylase that cleaves the γ-carboxyl-linked branching point of glutamylated tubulin. To date, pathogenic variants in AGBL5 have been associated only with isolated retinitis pigmentosa (RP). Hearing loss has not been reported in AGBL5-caused retinal disease.
View Article and Find Full Text PDFExploring non-coding regions is increasingly gaining importance in the diagnosis of inherited retinal dystrophies. Deep-intronic variants causing aberrant splicing have been identified, prompting the development of antisense oligonucleotides (ASOs) to modulate splicing. We performed a screening of five previously described deep-intronic variants among monoallelic patients with Usher syndrome (USH) or isolated retinitis pigmentosa.
View Article and Find Full Text PDFArticle Synopsis
- Hyperphosphatemia is common in peritoneal dialysis (PD) patients and can lead to poor health outcomes; researchers explored whether weekly creatinine clearance (CrCl) is a better indicator of serum phosphate levels compared to urea clearance.
- A study analyzed data from 16,796 PD patients across several institutions in North and South America, adjusting for various factors like age and gender, to determine the relationship between serum phosphate levels and both CrCl and urea Kt/V.
- The findings indicated that while CrCl did not outperform urea Kt/V in predicting serum phosphate levels, incorporating CrCl into predictive models improved their overall accuracy, suggesting its importance in managing phosphate levels in PD patients.
Article Synopsis
- * This review aims to identify key technologies that enable Industry 5.0 in the food sector by analyzing recent studies on innovative technology applications in food and agriculture, while also addressing the challenges and opportunities presented.
- * Findings indicate that Industry 5.0 represents an evolutionary shift rather than a revolutionary one, with technologies such as advanced AI, IoT, 4D printing, and digital twins poised to play significant roles in transforming the future of food.