Buprenorphine versus full agonist opioids for acute postoperative pain management: a systematic review and meta-analysis of randomized controlled trials.

Background/importance: Opioids continue to play a key role in managing acute postoperative pain, but their use contributes to adverse outcomes. Buprenorphine may offer effective analgesia with a superior safety profile.

Objective: To compare the efficacy and safety of buprenorphine with other opioids for acute postoperative pain management in adults.

Guadua angustifolia biochar/TiO composite and biochar as bio-based materials with environmental and agricultural application.

Globally, the companies that make commercial use of bamboo culms produce different kinds of solid waste rich in lignocellulosic biomass, which in some cases is not used and is discarded in landfills or incinerated in the open air; losing the possibility of recovering them and using them in other productive sectors. The research objective were to produce a biochar from Guadua agustifolia  Kunth sawdust, evaluate its potential environmental and agricultural use, obtain a biochar/TiO  composite to inactivate Escherichia coli and use the biochar as a soil conditioner in medicinal plants producing phenolic compounds and flavonoids. Biochar composite (produced at 300 °C for 1 h) involved TiO at 450 °C for 1 h for inactivation of E.

Inflammatory and Oxidative Patterns Regulated by Theracurmin Intake in an Experimental Model of Hypertrophic Training and Detraining.

Dietary supplements have improved performance and muscle hypertrophy in athletes and nonathletes in the past few decades. Theracurmin, a nutraceutical supplement based on curcumin, has been highlighted by its anti-inflammatory and antioxidant properties in physiological and pathological conditions. This study aimed to investigate the effects of theracurmin intake (300 mg/kg), containing 30 mg/kg of curcumin, in male Swiss mice (n = 66) under distinct protocols of climbing stairs (strength exercise) and their respective detraining period.

Analgesic efficacy of tapentadol in chronic joint disorders in horses: plasma serotonin concentration and adrenocortical response as biomarkers of pain-induced stress.

The study aimed to evaluate the analgesic efficacy of tapentadol in horses, by determining plasma serotonin concentration and adrenocortical response, as biomarkers of pain stress in chronic joint disorders. Thirty-six horses (20 females and 16 males) were divided into three groups of 12 subjects each: group A, osteoarthritis (OA), grade 3-4 lameness; group B, OA, grade 5 lameness; and group C, no OA, no lameness, were enrolled. The orthopedic examination included flexion tests, and radiological and ultrasound examinations.

Mineral composition in mussel and clam from Faro Lake of Messina: risk assessment for human health.

Bivalve are exposed to a wide range of contaminants, some of which may be toxic to human health. The aim of this study was to detect essential and non-essential elements such as Na, Ca, Mg, Cr, Mn, Fe, Ni, Cu, Zn, As, Cd, Pb, Hg, Be and Co in water, sediments, and and from Faro Lake. It is a lake of marine origin located on the northern coast of Messina (Sicily), where shellfish farming has been practiced for many years.