Publications by authors named "G M Cosenza"
Article Synopsis
- This study evaluates the effectiveness of adding dexmedetomidine (DEX) to Thoracic Paravertebral Block (TPVB) for managing postoperative pain in patients undergoing thoracic surgery.
- Six patients were monitored after receiving TPVB with ropivacaine, DEX, and methylene blue, focusing on pain levels and opioid use in the first 48 hours post-surgery.
- Results indicated that patients experienced low pain scores and reduced opioid consumption without significant side effects, suggesting DEX enhances the effectiveness of TPVB while methylene blue aids in ensuring proper anesthetic distribution.
Article Synopsis
- The study focuses on the Bagnolese sheep, a breed in Campania that produces milk for Pecorino Bagnolese cheese, and aims to analyze its milk production traits and the genetic impact of the DGAT1 gene.
- Researchers recorded milk quantity and assessed protein and fat content using specific methods, alongside genotyping to investigate genetic variations at DGAT1.
- Results indicated that Bagnolese sheep with the CT genotype at the g.5553 SNP of DGAT1 had higher fat and protein yields, suggesting this genotype could serve as a marker for improving milk production in the breed.
The αs2-casein is a phosphoprotein secreted in the milk of most mammals, and it is the most hydrophilic of all caseins. Contrary to genes found in ruminants, in donkeys two different encoding genes for donkey αs2-casein ( I and II) have been identified. However, unlike in ruminants, the variability at these loci has not been characterized in detail in donkeys until now.
View Article and Find Full Text PDFThe search for DNA polymorphisms useful for the genetic improvement of dairy farm animals has spanned more than 40 years, yielding relevant findings in cattle for milk traits, where the best combination of alleles for dairy processing has been found in casein genes and in . Nowadays, similar results have not yet been reached in river buffaloes, despite the availability of advanced genomic technologies and accurate phenotype records. The aim of the present study was to investigate and validate the effect of four single nucleotide polymorphisms (SNP) in the , , and genes on seven milk traits in a larger buffalo population.
View Article and Find Full Text PDFAmyotrophic lateral sclerosis (ALS) is the most frequent neurodegenerative disease of the motor system that affects upper and lower motor neurons, leading to progressive muscle weakness, spasticity, atrophy, and respiratory failure, with a life expectancy of 2-5 years after symptom onset. In addition to motor symptoms, patients with ALS have a multitude of nonmotor symptoms; in fact, it is currently considered a multisystem disease. The purpose of our narrative review is to evaluate the different types of pain, the correlation between pain and the disease's stages, the pain assessment tools in ALS patients, and the available therapies focusing above all on the benefits of cannabis use.
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