[The role of occupational factors in the development and course of respiratory sarcoidosis].

Aim: The aim of the study was to study the frequency of occurrence of exposure to harmful occupational factors in patients with sarcoidosis of the respiratory organs, depending on the course of the disease.

Materials And Methods: An open prospective study included 121 patients with sarcoidosis of the respiratory system from the age of 21 to 66 years, from 20072019. The diagnosis was histologically confirmed in all patients.

[Disorders of Vasoregulative Endothelial Function, Echocardiographic Assessment of Myocardial Dysfunction and Hemodynamics of Pulmonary Circulation in Cirrhosis of the Liver].

Aim: to study relationship between parameters of intracardiac hemodynamics assessed by Doppler echocardiography and functional activity of endothelium, hepatic blood flow and severity of portal hypertension in patients with cirrhosis of the liver (CL) of different etiology.

Results: We found that changes of structural and functional parameters of the heart in LC depended on the stage of compensation of portal hypertension and were accompanied by rearrangement of parameters of intracardiac hemodynamics. Pulmonary arterial hypertension (PAH) was found in 11.

Ultrastructural changes in cells of the gastric and small intestinal mucosa during bronchial asthma.

The complex of structural changes in the gastroduodenal mucosa in patients with bronchial asthma is considered as a polyetiological primary degenerative process with progressive atrophy of the epithelium and formation of erosions. Ultrastructural signs included degenerative changes in the endothelium of microvessels and surface and glandular epithelium, which were accompanied by compensatory hyperfunction of intact mucus-producing cells, hyperplasia, and increased functional activity of mast and immunocompetent cells. The development of destructive and erosive lesions was associated with hyperplasia of parietal and endocrine cells in the mucosa.

Norepinephrine induced contractions of the feline mesenterial vein under oxygenized and hypoxic conditions in vitro.

Cylindrical segments from mesenteric veins of 8 cats were prepared and mounted in a Krebs-Ringer tissue bath. The oxygenized solution was bubbled with 95% O2 and 5% CO2. For lowered oxygen tension 95% N2 and 5% CO2 was used.