[The effect of opiate receptor ligands on emotional cardiovascular reactions in lower primates].

Intravenous naloxone injection (0.1 mg/kg) facilitated blood pressure increase in response to conditioned sound stimulus followed by electrocutaneous shock in conscious chair-restrained baboons (Papio hamadryas). Naloxone at a dose of 1.

[Participation of the endogenous opioid system in the formation of the body's response to stress].

Autonomic responses to acute stressors in unanesthetized, chair-restrained baboons and macacas include elevations in heart rate, blood pressure and respiratory rate. Naloxone, in a dose of 1.0 mg/kg intravenously, as well as morphine (1.

Physically corrected orthogonal electrocardiographic lead systems in macaques and baboons.

The adequacy of various physically corrected electrocardiographic lead systems for lower primates was compared with the aid of physical models of the cardiac electrical field. Electrolytic tanks fashioned from plaster casts of the thorax of young adult male and female macaques and baboons were used. A dipole source situated at different points in the heart region simulated the electrical activity of the heart.

[Effect of naloxone in hypotension caused by acute blood loss in Papio hamadryas baboons].

Naloxone or physiological solution were injected in different doses to 11 baboons (Papio hamadryas) weighing 7-8 kg after bloodletting in a volume of 40% of the total amount of the blood. Naloxone effectively raised (in all the doses) the arterial blood pressure which dropped after bloodletting. The action of naloxone injected in small doses was more pronounced and had unique time parameters.

Emotional stress and the electrocardiogram.

The joint function of electrocardiographic cycle duration and of the spatial magnitude of the repolarization maximum vector, recorded with the physically corrected orthogonal lead system McFee-Parungao was used for studies of the effect of mental arithmetics in man and of emotional stimulation in unrestrained macaques. This approach allowed to distinguish between heart rate changes with and without signs of direct sympathetic stimulation of the working myocardium, and to study the correlation between emotionally induced effects on the pacemaker and on ventricular myocardial fibers. The latter was found to be much more expressed in macaques than in man.