Publications by authors named "G M Carlos"

Objectives: This study aimed to develop a liquid oral formulation containing losartan potassium, an angiotensin II receptor antagonist drug used for its antihypertensive activity, and to perform a preliminary stability assessment under different temperatures and packages to ensure paediatric therapeutic adherence and facilitate the hospital routine.

Methods: A syrup containing losartan potassium (1.0 and 2.

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Infantile colic is excessive crying for no apparent reason in an otherwise healthy infant. Although its physiopathology is not completely understood, therapies usually target gastrointestinal symptoms. This systematic review of randomized controlled trials (RCTs) analyzes the efficacy of lactase supplementation in infantile colic.

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Article Synopsis
  • Injured blood vessels in bone defects lead to low oxygen levels, which activate a pathway that promotes the growth of specific blood vessels (type H vessels) crucial for bone healing and remodeling.
  • These type H vessels interact with bone-forming cells to foster simultaneous development of blood and bone tissue, important for effective regeneration, particularly in procedures like distraction osteogenesis (DO).
  • The study aims to investigate if using deferoxamine (DFO) can revitalize these vital H vessels in irradiated bone, enhancing healing and speeding up the DO process, leading to more effective clinical treatments.
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