[Tumor markers p53, sFAS, FASL, CEA and CA 19-9 in evaluating the effectiveness of surgical and pharmaco nutritional treatment of patients with gastric cancer].

Unlabelled: The objective of this study is to develop a marker panel of abnormalities of immune regulatory systems and cell genome in patients with gastric cancer for assessment of efficacy of surgical treatment in combination with pharmaco-nutritional therapy in early postoperative period.

Materials And Methods: Expression of p53, sFAS, FASL, CEA, and CA 19-9, nutritial status, as well as incidence of purulent-septic complications in early postoperative period were determined in 40 patients with gastric cancer (21 patients--the test group and 19 patients--the comparative group) prior to a curative surgical intervention, postoperative days 1 and 7, while the pharmaco-nutritional therapy (the test group) or partial parenteral nutrition (the comparative group) has been performed.

Results: The pharmaco-nutritional therapy significantly decreases in activity of tumor suppressing genome, lymphocyte apoptosis, expression of oncology-associated markers, incidence of purulent-septic complications, as well as exacerbation risk for hypotrophy in patients with gastric cancer in early postoperative period.

[Urological and nephrological diseases in HIV-infected patients and drug addicts].

The article analyses literature on nephrological and urological pathology in HIV-infected and drug-addicted patients, compares original results of the treatment of nephrological and urological diseases in such patients, analyses clinical evidence, surgical interventions, causes of complications and lethal outcomes, indicates markers of renal insufficiency, proposes treatment policy which can improve treatment results of the above grave pathology.

[Clinical features of surgical diseases at the patients with HIV/AIDS].

Results of treatment of HIV-infected patients with surgical diseases are analyzed. These results are compared with ones at non-infected patients. The standards of surgical operations at HIV-infected patients are that permits to optimize surgical tactics at HIV/AIDS patients and to improve treatment results.

[Means for the prognosis and prevention of suppurative complications in intra-abdominal operations].

The authors describe the method of assessment of the immune and alimentary status by means of determination of the level of blood albumins and amount of lymphocytes. Preoperative detection of patients requiring immunocorrection and normalization of protein metabolism allows to carry out the corresponding therapy and to reduce the amount of postoperative complications.