Pulmonary pneumocytoma, formerly known as sclerosing hemangioma, is a rare, benign tumor that frequently affects women in the 4th and 5th decades of life. Here we present the case of a 17-year-old patient with a diagnosis of sclerosing pneumocytoma with infrequent presentation.
View Article and Find Full Text PDFis commonly mutated in cancer, giving rise to loss of wild-type tumor suppressor function and increases in gain-of-function oncogenic roles. Thus, inhibition of mutant p53 and reactivation of wild-type function represents a potential means to target diverse tumor types. ()-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one (NSC59984), first identified from a high-throughput screen, induces wild-type p53 signaling and antiproliferative effects while inhibiting mutant p53 gain-of-function activities.
View Article and Find Full Text PDFObjectives: Hospitalized children represent a vulnerable population with high rates of unidentified food insecurity (FI). We aimed to improve FI screening for eligible families from 0% to 60%. Secondarily, we sought to provide location-based food resources to families that screened positive.
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