Detecting Unique Analyte-Specific Radio Frequency Spectral Responses in Liquid Solutions-Implications for Non-Invasive Physiologic Monitoring.

With rising healthcare costs and the rapid increase in remote physiologic monitoring and care delivery, there is an increasing need for economical, accurate, and non-invasive continuous measures of blood analytes. Based on radio frequency identification (RFID), a novel electromagnetic technology (the Bio-RFID sensor) was developed to non-invasively penetrate inanimate surfaces, capture data from individual radio frequencies, and convert those data into physiologically meaningful information and insights. Here, we describe groundbreaking proof-of-principle studies using Bio-RFID to accurately measure various concentrations of analytes in deionized water.

[Pharmacologic profile of protirelin tartrate].

Pharmacological interest in the tripeptide thyrotropin-releasing hormone (TRH) is due to the multiple effects it produces. In fact, apart from taking part in regulating the activity of the hypothalamo-pituitary-thyroid axis, TRH produces various neuropharmacological effects which indicate a biological role that is probably more important than that of a releasing hormone. Trials performed in animals have shown, for example, the dose-dependent capacity of TRH to induce analgesia, probably by interacting with the opioid peptide system.

Maternal adrenalectomy and adult offspring in a conflict situation in the rat.

The effects of the absence of maternal adrenals during pregnancy (P), during lactation (L), during pregnancy and lactation (PL) were studied on pain suppressed behavior (punished drinking test) of the adult offspring in comparison with controls (C). The female L offspring showed a lower responsiveness to the anxiogenic stimulus, as demonstrated by increased water intake, decreased percentage of ineffective licks, and decreased time to perform 300 licks compared to C. The male L behavior was not affected.