[Screening in Cystic Fibrosis in the Chilean population. Pilot project for screening in newborns].

Unlabelled: Neonatal screening has been implemented internationally with different protocols and has become the routine method in the preclinical stage. Late diagnosis is associated with more severe symptoms with decreased survival and higher treatment costs.

Objectives: To estimate the incidence of cystic fibrosis; to evaluate the performance of the screening algorithms Immunoreactive Trypsinogen and Pancreatitis-Associated Protein (IRT/PAP) and the IRTxPAP product; to analyze the cut-off value for IRT, PAP, and IRTxPAP, and to establish a methodology for its ongoing evaluation; finally, to evaluate the quality of IRT and PAP measurements.

[Renal size in children with normal renal 99mTc-DMSA scan: building a nomogram with scintigraphic length].

Aim: The aim of this study was to evaluate renal size in children with normal 99mTc-DMSA scans and to compare it with the published ultrasonographic values.

Material And Methods: Renal length of DMSA normal scans obtained from 253 children with history of urinary tract infection was measured. Regression analysis and length/age curves were done.

[Methodological aspects related to the determination of the relative renal function using 99mTC MAG3].

Unlabelled: The aim of the study was to evaluate three different methods for calculating the split renal function in patients with only one functioning kidney, keeping in mind that the split function should be zero on the side of the non-functioning kidney.

Patients: We retrospectively selected 28 99mTc MAG3 renograms performed in children, 12 with unilateral nephrectomy, 4 with unilateral agenesis and 12 with a non-functioning kidney.

Methods: A renal and perirenal region of interest (ROI) were delineated around the functioning kidney.

Hepato-splenic distribution of 99Tcm-phytate and hepato-enteric distribution of 99Tcm-DISIDA in mice with carbon tetrachloride-induced acute liver damage.

The hepato-enteric distribution of 99Tcm-labelled DISIDA and the hepato-splenic distribution of 99Tcm-labelled phytate were studied in controls and in mice with carbon tetrachloride-induced acute liver damage. The test group animals showed a diminished excretion of DISIDA to intestine with retention of this tracer in the liver and an increased splenic uptake of phytate. No changes in the hepatic uptake of phytate were found.