Publications by authors named "G Lizard"
Phytosterols are plant sterols that are important secondary plant metabolites with significant pharmacological properties. Their presence in the plant kingdom concerns many unrelated botanical families such as oleageneous plants and cereals. The structures of phytosterols evoke those of cholesterol.
View Article and Find Full Text PDFAstrocytes specifically synthesize and release endozepines, a family of regulatory peptides including octadecaneuropeptide (ODN). We have previously reported that ODN rescues neurons and astrocytes from 6-OHDA-induced oxidative stress and cell death. The purpose of this study was to examine the potential implication of miR-34b, miR-29a, and miR-21 in the protective activity of ODN on 6-OHDA-induced oxidative stress and cell death in cultured rat astrocytes.
View Article and Find Full Text PDFArticle Synopsis
- Milk thistle seed oil, derived from Silybum marianum and the lesser-known Silybum eburneum, is being investigated for its health benefits, particularly in antioxidant properties.
- This study compares the lipid and phenolic profiles of the seed oils from both species and highlights their high content of unsaturated fatty acids and beneficial phytosterols.
- The oils demonstrated strong antioxidant activities, protecting THP-1 cells from oxidative stress linked to age-related diseases, suggesting they may be valuable for nutrition and disease prevention.
Article Synopsis
- - Neuroinflammation is linked to serious central nervous system disorders and is often caused by oxidative stress, which leads to cell death, making it a vital target for treatment.
- - Apigenin, a nutraceutical found in various fruits, vegetables, and herbs, has potential anti-inflammatory properties that could help in managing conditions like multiple sclerosis, Parkinson's, Alzheimer's, and other health issues.
- - The review highlights significant studies on apigenin's effects on neuroinflammation and advocates for more research into its potential clinical uses.
Article Synopsis
- The study analyzes the phytochemical composition of wild edible Mediterranean plants, focusing on their mineral, sugar, organic acid, polyphenolic contents, and antioxidant potential.
- It finds that both species have varying levels of essential minerals and sugars across different organs, with seeds showing higher antioxidant activity.
- The research highlights the nutritional value of these plants, suggesting their potential use in functional food development due to their rich nutrient profile and antioxidant properties.