Publications by authors named "G Lilja"
Purpose: Hyperoxemia is common in patients resuscitated after out-of-hospital cardiac arrest (OHCA) admitted to the intensive care unit (ICU) and may increase the risk of mortality. However, the effect of hyperoxemia on functional outcome, specifically related to the timing of exposure to hyperoxemia, remains unclear.
Methods: The secondary analysis of the Target Temperature Management 2 (TTM-2) randomized trial.
Article Synopsis
- * Results showed a significant increase in good functional outcomes, from 35% to 64%, and improvements in physical HRQoL, while mental HRQoL remained stable over the year.
- * Factors like increasing age, lower clinical frailty, lack of diabetes, and shorter mechanical ventilation periods were linked to better functional outcomes and physical HRQoL at 12 months.
Background: The aim of this study was to assess whether hypothermia increased survival and improved functional outcome when compared with normothermia in out-of-hospital cardiac arrest (OHCA) patients with similar characteristics than in previous randomized studies showing benefits for hypothermia.
Methods: Post hoc analysis of a pragmatic, multicenter, randomized clinical trial (TTM-2, NCT02908308). In this analysis, the subset of patients included in the trial who had similar characteristics to patients included in one previous randomized trial and randomized to hypothermia at 33 °C or normothermia (i.
Article Synopsis
- The study aimed to evaluate physical activity levels six months post-out-of-hospital cardiac arrest (OHCA) and identify risk factors for low activity levels.
- In a follow-up with 807 OHCA survivors across Europe, Australia, and New Zealand, 34% reported low physical activity, while 44% were moderately active and 22% highly active.
- Significant risk factors for low physical activity included obesity, mobility issues, and cognitive impairment.
Article Synopsis
- Airway management is vital in treating out-of-hospital cardiac arrest (OHCA), focusing on whether tracheal intubation (TI) or supraglottic airway devices (SGA) lead to better patient outcomes.
- A secondary analysis of the TTM2 trial included 1702 adult OHCA patients and found that most (71.6%) received TI, while 28.4% were managed with SGA.
- Results indicated that the type of airway management did not significantly affect outcomes like ventilator-free days, neurological status, or mortality rates after 26 days.