Publications by authors named "G Leung"
Objectives: This study aimed to evaluate the effectiveness of interventions in reducing loneliness among community-dwelling older adults.
Design: A network meta-analysis (NMA) and systematic review.
Setting And Participants: Interventional studies were included if they contained original quantitative data on interventions to reduce loneliness among community-dwelling older adults.
Article Synopsis
- The study explored the link between Crohn's disease activity, fatigue, and neurocognitive function in adults, comparing 25 patients with Crohn's to 26 healthy controls.
- Patients with Crohn's disease reported significantly higher levels of fatigue, particularly when symptomatic, but showed no differences in neurocognitive accuracy or speed compared to healthy individuals.
- However, those with active Crohn's disease had slower response times in social cognition and episodic memory tasks, indicating a relationship between disease activity and cognitive processing, regardless of fatigue levels.
Natural compounds demonstrate unique therapeutic advantages for cancer treatment, primarily through direct tumor suppression or interference with the tumor microenvironment (TME). Glycyrrhizic acid (GL), a bioactive ingredient derived from the medicinal herb Glycyrrhiza uralensis Fisch., and its sapogenin glycyrrhetinic acid (GA), have been recognized for their ability to inhibit angiogenesis and remodel the TME.
View Article and Find Full Text PDFComparative Effectiveness of Antivirals and Monoclonal Antibodies for Treating COVID-19 Patients Infected With Omicron Variant: A Systematic Review and Network Meta-Analysis.
Influenza Other Respir Viruses
December 2024
Antiviral drugs likely remain effective against the SARS-CoV-2 Omicron variant, while monoclonal antibody (mAb) therapies have experienced drops in neutralizing ability. This systematic review and network meta-analysis aims to estimate the comparative effectiveness of antivirals and mAb therapies for treating COVID-19 patients infected with Omicron, capturing primarily acute outcomes. We searched multiple databases from July 4 to July 19, 2022, with updates through November 4, 2022.
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