Publications by authors named "G Leleu"
Smoked salmon and smoked trout are ready-to-eat and potentially contaminated with the pathogenic bacterium making them high risk for the consumer. This raises questions about the presence of hypervirulent or persistent strains in the salmon and trout industries. Knowledge of the genetic diversity of circulating strains in these sectors is essential to evaluate the risk associated with this pathogen and improve food safety.
View Article and Find Full Text PDFThe objectives of this study were 1) to evaluate the impact of two industrial disinfectants on the viability of Listeria monocytogenes populations in biofilm and 2) to investigate the viability state of L. monocytogenes cells present on contact surfaces in the smoked salmon processing environment. In the first step, we cultured mono species and mixed species biofilms containing L.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate how effective different sampling methods (contact plates, sponges, and swabs) are in recovering biofilm populations of Listeria monocytogenes in various seafood environments.
- Different materials and fish types (smoked salmon and cod) were tested, revealing that bacteria adhered differently based on the conditioning material.
- The results showed that while the sampling methods all recovered similar amounts of viable bacteria, the effectiveness varied based on their ability to detach different bacterial states, underscoring the relevance of sampling methods in food safety.
Article Synopsis
- Ready-to-eat food products can become contaminated by harmful bacteria during processing, which may form protective biofilms in industrial environments.
- To monitor bacterial contamination, food industry professionals need to regularly sample surfaces for pathogens like Listeria monocytogenes and spoilage bacteria such as Pseudomonas fluorescens.
- A 2010 survey across 14 EU states revealed that professionals prefer friction sampling methods (using gauze pads, swabs, and sponges) over contact methods; however, recent comparisons showed no significant difference in effectiveness between these methods for recovering the target bacteria from biofilms.
Background: Triple combination therapy based on a ritonavir (RTV)-boosted protease inhibitor plus two nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) has improved outcomes in HIV type-1 (HIV-1)-infected patients. For patients unable to tolerate these regimens, alternative therapeutic approaches are needed.
Methods: We report a comparative, open-label study in treatment-naive patients who underwent initial induction treatment with a triple combination including RTV-boosted atazanavir (ATV; 300/100 mg once daily).