Publications by authors named "G Leanza"
Article Synopsis
- * Treatment focuses on reducing spleen size and alleviating symptoms, with patients evaluated as lower or higher risk for transplant eligibility; those not eligible usually receive long-term JAK inhibitor therapy.
- * Newer JAK inhibitors and combination treatments are under investigation to address the limitations of current therapies, such as limited efficacy and adverse effects, highlighting the need for ongoing research in this area.
A case of tuberculous and Listeria-associated lymphadenitis in a migrant from Mexico.
Diagn Microbiol Infect Dis
January 2025
Tuberculous lymphadenitis is one of the most common extrapulmonary manifestation of tuberculosis. Lymphadenitis due to Listeria monocytogenes is rarely described. We present a case of a 59-year-old woman from Mexico presented to the Emergency Department with a 2-week history of erythematous and painful swelling in the right retromandibular area.
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- This study examined the effects of D-VTd induction therapy on recovery after autologous stem cell transplantation in patients with newly diagnosed multiple myeloma (NDMM).
- Sixty patients received D-VTd while 80 others received VTd as a control, with results showing that D-VTd led to a slightly longer time for neutrophil and platelet recovery.
- Despite delayed engraftment in the D-VTd group and a higher incidence of febrile neutropenia, the study concluded that D-VTd does not negatively affect overall transplant safety outcomes.
Introduction: Dalbavancin is an antibiotic characterized by an extended half-life and efficacy against methicillin-resistant Staphylococci. Currently, there are only narrative reviews summarizing the evidence about the use of dalbavancin for infective endocarditis (IE), many of which are focused primarily on its use as consolidation therapy. For this reason, we conducted a systematic review to describe the clinical efficacy and the safety of dalbavancin in IE treatment.
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- The study investigates the effects of a high-fiber diet on bone health and glucose control in type 2 diabetes mellitus (T2DM) patients, highlighting the need for effective interventions to address bone fragility associated with T2DM.* -
- After 12 weeks, the high-fiber diet group showed significant improvements in body mass index (BMI) and blood sugar control (HbA1c), but also a decrease in a marker for bone formation, suggesting potential negative effects on bone health.* -
- Despite these changes in metabolic health and reduced bone formation markers, there were no significant differences found in bone structure or gene expression related to bone health between the high-fiber diet group and the control group.*