Publications by authors named "G La Vecchia"

Cardiogenic shock (CS) is a life-threatening condition. The aim of this study is to evaluate the clinical characteristics, management, and complication rate of patients with CS admitted to a high-volume hospital in Italy. We retrospectively reviewed the clinical, echocardiographic, and laboratory data, therapeutic management, and outcomes of patients with CS admitted to the Policlinico Gemelli (Rome) between January 1, 2020, and January 1, 2023.

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Article Synopsis
  • Coronary microvascular dysfunction (CMD) is important in heart failure (HF) development and progression, but its mechanisms remain complex and unclear.
  • Key factors contributing to CMD include chronic inflammation, oxidative stress, and neurohormonal activation.
  • Currently, there are no specific treatments for CMD, and diagnosing it can be challenging; this review will explore the connections between CMD and HF, their implications, and potential treatment opportunities.
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Previous studies reported a robust relation between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD). Systemic inflammation has been proposed as possible pathogenetic mechanism linking these 2 entities, although data on atherosclerotic coronary features in COPD patients are lacking. We studied atherosclerotic coronary plaque features in COPD patients presenting with acute coronary syndrome (ACS) using optical coherence tomography (OCT).

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