A concise synthesis of -bicyclo[6.1.0]nonyne carboxylic acid.

Bicyclo[6.1.0]nonyne carboxylic acid (BCN-COOH) is a valuable intermediate for the development of bioorthogonal click reagents.

RGB-Single-Chip OLEDs for High-Speed Visible-Light Communication by Wavelength-Division Multiplexing.

Organic light-emitting diodes (OLEDs) have been developed for high-speed transmitters of visible-light communication (VLC) but so far the possibility of direct fabrication of multiple colors on a single substrate has not been exploited for multi-Gbps data transmission. Very fast red-, green-, and blue (RGB)-emitting OLEDs are developed on a single substrate to realize high data transmission speed by wavelength division multiplexing (WDM). -6 dB electrical bandwidth of over 100 MHz is achieved for all colors by selecting fluorescent materials with nanosecond emission lifetimes and little overlap between their emission spectra and incorporating them into OLEDs designed for high-speed operation.

Risk factors for femoral stem fracture following total hip arthroplasty: a systematic review and meta analysis.

Background: Femoral stem fracture following total hip arthroplasty (THA) is an infrequent but nevertheless devastating complication, with an increasing worldwide prevalence as demand for primary THA continues to increase. The aim of this study was to perform a systematic review and meta-analysis of risk factors for femoral stem fracture to help identify at risk patients.

Methods: A systematic search was conducted on EMBASE, MEDLINE and AMED to identify relevant studies.

Experience of an anatomic femoral stem in a UK orthopaedic centre beyond 20 years of follow-up.

Introduction: Increasing interest in the use of anatomical stems has developed as the prevalence of periprosthetic fractures (PPFs) continues to increase. The primary aim of this study was to determine the long-term survivorship and PPF rate of an anatomical femoral stem in a single UK centre.

Patients And Methods: Between 2000 and 2002, 94 consecutive THAs were performed using the 170 mm Lubinus SP II anatomical femoral stem in our institution.

Fluorescence lifetime imaging for explosive detection.

In this Letter, a time-resolved 120 × 128 pixel single-photon avalanche diode (SPAD) sensor is used in conjunction with an array of organic semiconductor films as a means of detecting the presence of explosive vapors. Using the spatial and temporal resolution of the sensor, both fluorescence intensity and fluorescence lifetime can be monitored on a pixel-by-pixel basis for each of the polymer films arranged in a 2 × 2 grid. This represents a significant improvement on similar systems demonstrated in the past, which either offer spatial resolution without the temporal resolution required to monitor lifetime or offer only a single bulk measurement of lifetime and intensity without the spatial resolution.