Publications by authors named "G L Simmons"
Background: Approximately two percent of the world's population are affected by intracranial aneurysms (IAs). This study aimed to evaluate literature regarding presentation, treatment and outcomes of ruptured IAs in Africa.
Methods: A systematic review of the literature using PubMed/MEDLINE, SCOPUS, Web of Science and Google Scholar databases was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Article Synopsis
- Hemifacial spasm (HFS) is a rare disorder causing involuntary facial muscle contractions, and this review compares two surgical techniques—transposition and interposition—for treating it.
- A systematic search of medical databases led to the inclusion of 62 studies, with both techniques showing similar rates of spasm freedom at follow-ups (around 90%) and comparable complication rates.
- While both techniques are deemed safe and effective for microvascular decompression, the reviewed literature does not conclusively favor one method over the other in terms of safety or efficacy.
Background: Autistic youth experience high rates of anxiety, which has been treated with modified cognitive-behavioral therapy (CBT), often integrating exposure therapy. Such anxiety treatments are effective for this population; however, there remains a gap between these evidence-based mental health interventions and their implementation in community mental health (CMH) services where autistic youth receive care.
Method: This qualitative study conducted semi-structured interviews with four types of community members in the United States: 15 autistic youth with anxiety, 15 caregivers of autistic youth with anxiety, 11 CMH clinicians, and 8 CMH clinic leaders.
Article Synopsis
- A Phase II clinical trial examined the effects of intravenous vitamin C on patients receiving hematopoietic stem cell transplants to reduce nonrelapse mortality (NRM).
- Patients (55 total) were given IV vitamin C for 14 days, which corrected their initial vitamin C deficiency and showed a trend towards lower NRM (11%) compared to historical controls (25%).
- The study suggests that vitamin C repletion is safe and may improve survival rates (82% vs. 62%), but further randomized trials are necessary to validate these findings.
This video depicts a left-sided MRI-guided focused ultrasound (MRgFUS) thalamotomy for a right-arm tremor in a 76-year-old, right-handed man with bilateral upper-extremity tremors. The patient tolerated the procedure well, with immediate tremor reduction that persisted at the 1-month follow-up, and there were no adverse events noted during intraoperative testing, postoperative testing, or follow-up. This case highlights MRgFUS as an effective, safe, incision-free treatment option for medically refractory essential tremor.
View Article and Find Full Text PDF