Publications by authors named "G L Salvagno"

Background: Minimizing air aspiration by carefully filling blood gas syringes is crucial to prevent air contamination from causing undesirable variations in gasses and other molecules. While some previous studies investigated this aspect, these are now outdated and only analyzed a limited number of blood gas parameters. Thus, we investigated the effects air contamination in the syringe using a modern blood gas analyzer.

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Background And Aims: The aim of this study was to investigate the possible preanalytical effect of incomplete filling of blood tubes on molecular biology assays.

Materials And Methods: The study population consisted of 13 healthy volunteers from whom 11 mL of whole blood was collected and then distributed in different volumes (1.5, 3.

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Article Synopsis
  • The study aimed to explore how contaminating venous blood samples with lipid solutions affects measurements from blood gas analyzers.
  • Blood samples were collected from 17 healthcare workers with varying percentages (0%, 5%, and 10%) of lipid solution, and analyzed quickly for blood gas parameters and triglyceride levels.
  • Results showed that higher lipid contamination significantly altered various analytes, indicating that contamination can lead to clinically relevant inaccuracies in blood gas analysis, suggesting the need for improved blood gas analyzers that include serum indices.
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We planned a series of experiments to investigate the possible role of spike protein of different SARS-CoV-2 variants in influencing erythrocyte biology. The values of erythrocyte count, hemoglobin, and mean corpuscular hemoglobin (MHC) did not vary across all samples challenged with both concentrations of the four different SARS-CoV-2 recombinant spike proteins. A significant increase in mean corpuscular volume (MCV) was observed with the recombinant SARS-CoV-2 Alpha and Delta spike proteins at both 2 and 20 ng/mL final concentrations.

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