Group therapy with the antisocial spinal-cord-injured patient.

This conceptual article attempts to help health care professionals deepen their understanding of the psychological characteristics of antisocial spinal cord-injured patients that predispose them to injury, being a disruptive influence on the medical floor, oppositional acting out with physicians, and potentially thwarting effective treatment. Group techniques are described that appear to improve the adaptation of these patients to their traumatic injury and hospital environment.

Natural killer cell profile of two random-bred strains of athymic rats.

We have demonstrated that Rowett and NIH strains of random-bred athymic and euthymic rats exhibited significant levels of natural killer (NK) cell cytotoxicity against various murine and human tumor cell lines. Rats of both strains displayed high NK cell cytotoxicity in peritoneal exudate, peripheral blood and spleen, and lower activities in lung and liver. No activity was detected in bone marrow.

Histologic classification as an indication of therapeutic response in malignant lymphoma of dogs.

In retrospective evaluation of treatment of canine malignant lymphoma, 12 of 13 dogs that had received doxorubicin alone or in combination with dacarbazine attained complete remission. Doxorubicin had been given alone, with combination chemotherapy being used only when complete remission could not be achieved and maintained with doxorubicin. The response to single or combined chemotherapy was correlated with histologic cell type of the malignant lymphoma.

Rescue by peripheral blood mononuclear cells in dogs from bone marrow failure after total-body irradiation.

In order to determine the minimum dose of buffy coat cells necessary to achieve hematopoietic rescue following supralethal irradiation, mongrel dogs under general anesthesia were subjected to leukacytapheresis using three different techniques of cell separation. The buffy coats were frozen with dimethylsulfoxide and stored at -196 degrees C until transfused. Sixteen dogs were irradiated with 800 rads and were supported with antibiotics and transfusions of irradiated homologous blood.