Publications by authors named "G L Randall"

Background: Demineralized bone matrix (DBM) is a commonly utilized allogenic bone graft substitute to promote osseous union. However, little is known regarding outcomes following DBM utilization in foot and ankle surgical procedures.

Aim: To evaluate the clinical and radiographic outcomes following DBM as a biological adjunct in foot and ankle surgical procedures.

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Staphylococcus aureus is a major cause of infections like bacteremia, pneumonia, and endocarditis. These infections are often linked to the ability of S. aureus to form biofilms.

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Lanthipeptides are ribosomally synthesized and post-translationally modified peptides that bear the characteristic lanthionine (Lan) or methyllanthionine (MeLan) thioether linkages. (Me)Lan moieties bestow lanthipeptides with robust stability and diverse antimicrobial, anticancer, and antiallodynic activities. Installation of (Me)Lan requires dehydration of serine and threonine residues to 2,3-dehydroalanine (Dha) and ()-2,3-dehydrobutyrine (Dhb), respectively.

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Background: The purpose of this systematic review was to evaluate outcomes following intra-articular injection of hyaluronic acid (HA) for the treatment of hallux rigidus.

Methods: During April 2024, a systematic review of the MEDLINE, EMBASE, and Cochrane Library databases was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data collected and analyzed were number of patients, patient age, follow-up, subjective clinical outcomes, complications, and failures.

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Article Synopsis
  • This study aimed to investigate how common osteochondral lesions (OCLs) are in the lateral talar dome among patients with anterior ankle impingement who also have a thickened segment of the anterior tibio-fibular ligament.
  • Researchers reviewed the cases of 40 patients who underwent arthroscopy for ankle impingement, assessing various clinical outcomes before and after surgery.
  • The results showed that 90.6% of patients had a hypertrophic ligament, and 75.9% had OCLs, with postoperative scores improving significantly, indicating a link between the ligament thickness and the presence of OCLs.
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