Publications by authors named "G L Ramirez-Villar"
Introduction: Introduction: Renal cell carcinoma (RCC) is a very rare pediatric renal tumor. Robust evidence to guide treatment is lacking and knowledge on targeted therapies and immunotherapy is mainly based on adult studies. Currently, the International Society of Pediatric Oncology-Renal Tumor Study Group (SIOP-RTSG) 2016 UMBRELLA protocol recommends sunitinib for metastatic or unresectable RCC.
View Article and Find Full Text PDFBackground: Among patients with nephroblastoma, those with bilateral disease are a unique population where maximising tumour control must be balanced with preserving renal parenchyma.
Methods: The SIOP 2001 protocol recommended surgery after neoadjuvant cycle(s) of Dactinomycin and Vincristine (AV) with response-adapted intensification, if needed. Adjuvant treatment was given based on the lesion with the worst histology.
Article Synopsis
- Congenital mesoblastic nephroma is the most common solid kidney tumor in newborns, and MRI is the preferred method for diagnosis, especially in differentiating it from Wilms tumor.
- This study involved a review of MRI scans from 52 confirmed cases of congenital mesoblastic nephroma, categorizing them into classic, cellular, and mixed types, with a focus on their distinct MRI characteristics.
- Key findings revealed that the classic type was more homogeneous and smaller, while cellular and mixed types were larger and more heterogeneous, with specific MRI signaling patterns noted across all cases.
Introduction: ECLIM-SEHOP platform was created in 2017. Its main objective is to establish the infrastructure to allow Spanish participation into international academic collaborative clinical trials, observational studies, and registries in pediatric oncology. The aim of this manuscript is to describe the activity conducted by ECLIM-SEHOP since its creation.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic had global catastrophic effects on the management of non-communicable diseases including paediatric cancers. Restrictions during the start of 2020 complicated timely referrals of patients to specialized centres. We aimed to evaluate the pandemic's impact on the number of new diagnoses, disease characteristics and management delay for paediatric renal tumour patients included in the SIOP-RTSG-UMBRELLA study, as compared with data from a historical SIOP-RTSG trial (2005-2009).
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