Publications by authors named "G L Lehmann"
Article Synopsis
- RNA binding proteins (RBPs) are essential for gene regulation by recognizing specific RNA targets, and various methods exist to study their binding preferences, like CLIP and SELEX.
- Current methods face challenges such as the need for purified proteins and extensive sequencing, which can limit their usage.
- The proposed RNA bind-n-seq method simplifies the process by using random RNA pools and allows for multiple selection rounds, improving motif identification without needing recombinant proteins.
Spillback effects of the parasitic salmon louse from fish farms to wild fish are a critical environmental concern for countries with wild salmon. The ectoparasitic louse causes significant physical and physiological damage to wild salmonids that probably have long-term impacts on individuals and population dynamics. However, empirical links between injuries and abundance of lice have not been established in the wild.
View Article and Find Full Text PDFAims: Diabetes distress is common among people with type 1 diabetes (T1D), negatively affecting quality of life, self management, and diabetes outcomes. E-health-based interventions could be an effective and low-cost way to improve the psychological care for people with T1D experiencing diabetes distress. The MyREMEDY study aims to test the effectiveness of the online unguided self-help intervention MyDiaMate in decreasing diabetes distress in adults with T1D.
View Article and Find Full Text PDFExposure to polychlorinated biphenyls (PCBs) remains a potential human health risk due to their persistence in the environment, despite a global ban on their production. Understanding the composition of PCB mixtures is essential for the application of a mixtures-based approach to assessing health risks of PCB exposure. This work represents the most extensive effort to date to compile and make publicly available the PCB congener profiles for mixtures with toxicological data, providing a foundation for understanding toxicological potency of PCB mixtures in the environment.
View Article and Find Full Text PDFObjectives: Rheumatoid arthritis (RA) is associated with an increased risk for osteoporosis and osteoporotic fractures. Since the treatment of RA has improved significantly in recent years, we can expect RA-associated osteoporosis to decrease with good disease control. Therefore, we conducted a retrospective study to investigate whether the frequency of osteoporosis and osteoporotic fractures has changed during 24 years in RA.
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