Dengue severity by serotype and immune status in 19 years of pediatric clinical studies in Nicaragua.

Background: Dengue virus, a major global health threat, consists of four serotypes (DENV1-4) that cause a range of clinical manifestations from mild to severe and potentially fatal disease.

Methods: This study, based on 19 years of data from the Pediatric Dengue Cohort Study and Pediatric Dengue Hospital-based Study in Managua, Nicaragua, investigates the relationship of serotype and immune status with dengue severity. Dengue cases were confirmed by molecular, serological, and/or virological methods, and study participants 6 months to 17 years old were followed during their hospital stay or as ambulatory patients.

Plant Microbe Interaction-Predicting the Pathogen Internalization Through Stomata Using Computational Neural Network Modeling.

Foodborne disease presents a substantial challenge to researchers, as foliar water intake greatly influences pathogen internalization via stomata. Comprehending plant-pathogen interactions, especially under fluctuating humidity and temperature circumstances, is crucial for formulating ways to prevent pathogen ingress and diminish foodborne hazards. This study introduces a computational model utilizing neural networks to anticipate pathogen internalization via stomata, contrasting with previous research that emphasized biocontrol techniques.

Psychometric properties of the Chinese version of the sport success scale: a confirmatory study on Chinese adolescents.

Background: Sporting success relies not only on athletes' physical qualities but also involves psychological, technical, and environmental factors. Given the lack of effective tools to comprehensively measure sporting success in the Chinese context, this study aimed to validate the Chinese version of the Sport Success Scale (SSS-C).

Methods: A total of 604 adolescent basketball players, comprising 301 (49.

Serotype-specific epidemiological patterns of inapparent versus symptomatic primary dengue virus infections: a 17-year cohort study in Nicaragua.

Background: Dengue is the most prevalent mosquito-borne viral disease and a major public health problem worldwide. Most primary infections with the four dengue virus serotypes (DENV1-4) are inapparent; nonetheless, whether the distribution of symptomatic versus inapparent infections by serotype varies remains unknown. Here, we present (1) the evaluation of a DENV1-4 envelope domain III multiplex microsphere-based assay (EDIII-MMBA) to serotype inapparent primary infections and (2) its application leveraging 17 years of prospective sample collection from the Nicaraguan Pediatric Dengue Cohort Study (PDCS).

Validation and measurement invariance of the Chinese version of the academic self-efficacy scale for university students.

Objectives: The objective of this study was to examine the psychometric properties of the Chinese version of the Academic Self-Efficacy Scale (ASES-C) and confirm its measurement invariance across gender identities.

Methods: In this study, 502 university students (29.68% male, 70.