Publications by authors named "G L Hoff"

Article Synopsis
  • A cross-sectional study in Norway examined adverse events related to colonoscopy in a randomized colorectal cancer screening trial, involving over 10,000 participants.
  • Out of those, 2.4% experienced adverse events, ranging from mild to severe, with the most common issues being gastrointestinal bleeding and abdominal pain.
  • Key risk factors for adverse events included older age, female sex, and specific medical treatments, highlighting the importance of awareness for endoscopists to reduce risks.
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Article Synopsis
  • Different countries have different rules for how positive results are determined in poop tests for colorectal cancer (CRC) screening.
  • In a study with Norwegian people aged 50-74, they looked at the number of colonoscopies (a procedure to check the colon) at various poop test thresholds.
  • They found that higher thresholds mean fewer colonoscopies but also less chance of finding serious issues like cancer, and the risk of problems during the colonoscopy increases with higher thresholds.
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We have previously demonstrated an association between increased abundance of and colorectal cancer (CRC) and adenomas in two independent Norwegian cohorts. Here we seek to verify our previous findings using new cohorts and methods. In addition, we characterize lifestyle and sex specificity, the functional potential of the species, and their interaction with other microbial species.

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Background And Study Aims: Long-time follow-up of sigmoidoscopy screening trials has shown reduced incidence and mortality of colorectal cancer (CRC), but inadequate bowel cleansing may hamper efficacy. The aim of this study was to assess the impact of bowel cleansing quality in sigmoidoscopy screening.

Patients And Methods: Individuals 50 to 74 years old who had a screening sigmoidoscopy in a population-based Norwegian, randomized trial between 2012 and 2019, were included in this cross-sectional study.

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Background: Despite adequate hormone substitution in Hashimoto disease, some patients may have persistent symptoms with a possible autoimmune pathophysiology. A recent randomized trial (RCT) using patient-reported outcome measures as the primary endpoint showed benefit in total thyroidectomy, but at a cost of high complication rates.

Objective: To verify results from the RCT in an observational study including a wider range of patients and explore means of predicting who may benefit from such surgery.

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