Publications by authors named "G L Curran"

Background: Delirium is a complex neuropsychiatric syndrome characterised by an acute state of confusion, with a substantial impact on medical inpatients. Despite its growing recognition as a global healthcare concern, delirium remains underdiagnosed, partly due to a lack of awareness among healthcare professionals. The aim of this study was to explore how healthcare professional students experience caring for individuals experiencing delirium, the influence of their current pre-registration healthcare education, and importance of interprofessional teamwork in their role.

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Background: Sodium zirconium cyclosilicate (SZC) reduces serum potassium in patients with chronic hyperkalaemia in clinical trials, but its role in the emergency treatment of hyperkalaemia is unproven. We hypothesized that SZC use for emergent hyperkalaemia would be associated with a reduction in rates of emergency interventions for hyperkalaemia.

Methods: This was a single-centre, propensity score-weighted case-control study of patients admitted with hyperkalaemia to a specialist renal centre.

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  • * The HDL mimetic peptide 4F shows promise as a treatment, as it significantly reduces the blood-to-brain influx of Aβ in both wild-type and APP/PS1 transgenic mice.
  • * 4F lowers Aβ-induced activation of the p38 pathway in endothelial cells, suggesting it may help protect the BBB and reduce Aβ accumulation, offering potential therapeutic avenues for AD.
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  • Interprofessional education is essential for healthcare students to learn teamwork and improve patient care, but it's often underrepresented in curricula, leading to the study that engaged students from various health professions in creating a resource on delirium management.* -
  • Two workshops were held with students from medical, nursing, pharmacy, and occupational therapy programs, involving activities like resource creation and discussions, with follow-up focus groups to assess experiences during the co-design process.* -
  • Key outcomes included enhanced relationships among students, a deeper understanding of interprofessional collaboration, and boosted professional confidence, resulting in valuable peer learning and skill development in managing delirium.*
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Background: The gold-standard treatment for opioid use disorder (OUD) is medication for OUD (MOUD). However, less than a quarter of people with OUD initiate MOUD. Expanding the Collaborative Care Model (CoCM) to include primary care patients with OUD could improve access to and initiation of MOUD.

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