Reaching the target dose with one single I-mIBG administration in high-risk neuroblastoma: The determinant impact of the primary tumour.

Background: I-metaiodobenzylguanidine ( I-mIBG) effectiveness in children with metastasised neuroblastoma (NB) is linked to the effective dose absorbed by the target; a target of 4 Gy whole-body dose threshold has been proposed. Achieving this dose often requires administering I-mIBG twice back-to-back, which may cause haematological toxicity. In this study, we tried identifying the factors predicting the achievement of 4 Gy whole-body dose with a single radiopharmaceutical administration.

A framework for FAIR robotic datasets.

It is essential to publish and make available environmental data gathered by emerging robotic platforms to contribute to the Global Ocean Observing System (GOOS), supported by the United Nations - Decade of Ocean Science for Sustainable Development (2021-2030). The transparency of these unique observational datasets needs to be supported by the corresponding robotic records. The data describing the observational platform behaviour and its performance are necessary to validate the environmental data and repeat consistently the in-situ robotic deployment.

An engineered glove to follow finger function in rheumatoid arthritis: an observational prospective study.

The engineered Hand Test System (HTS) glove has shown high reliability in assessing the baseline functional status of rheumatoid arthritis (RA) hand. Starting from this achievement, the aim of the present observational prospective study was to assess the functionality of the single fingers of rheumatoid hand at follow-up. Eighty RA patients performed HTS glove tests at baseline and among these fifty-six patients were re-tested after 7 months.

Patient safety in emergency departments: a problem for health care systems? An international survey.

Background And Importance: Patient safety in healthcare is one of the cornerstones of quality of care. The emergency department (ED) is by its very nature a place where errors and safety issues are liable to occur.

Objective: The aim of the study was to assess health professionals' perception of the level of safety in EDs and to identify in which work domains safety appears most at risk.

Underwater Drone Architecture for Marine Digital Twin: Lessons Learned from SUSHI DROP Project.

The ability to observe the world has seen significant developments in the last few decades, alongside the techniques and methodologies to derive accurate digital replicas of observed environments. Underwater ecosystems present greater challenges and remain largely unexplored, but the need for reliable and up-to-date information motivated the birth of the Interreg Italy-Croatia SUSHI DROP Project (SUstainable fiSHeries wIth DROnes data Processing). The aim of the project is to map ecosystems for sustainable fishing and to achieve this goal a prototype of an Unmanned Underwater Vehicle (UUV), named Blucy, has been designed and developed.