To understand the interactions of entomopathogenic fungi with forage plants and their influence on associated herbivorous, we evaluated the influence of endophytic colonization with three isolates (CEPAF_ENT 25, CEPAF_ENT 27, and IBCB 425) of Metarhizium anisopliae on Cynodon dactylon, regarding the biological and behavioral aspects of Collaria scenica, an emerging sucking pest in pastoral systems in Brazil. The application of suspensions at the base of plant (drench) was effective in promoting endophytic colonization, especially in the roots, with emphasis on isolates CEPAF_ENT25 and CEPAF_ENT27. Despite the significant reduction in damage caused by C.
View Article and Find Full Text PDFIntroduction: Advances in imaging methods have led to an increasingly frequent diagnosis of adrenal gland lesions as incidental findings. Despite progress in this field, there is still limited information regarding the epidemiology of the clinical and metabolic profile of patients with adrenal incidentaloma (AI). The objective is analyze the epidemiology of adrenal tumors at Gaffrée e Guinle University Hospital (HUGG) and compare it with data from the literature.
View Article and Find Full Text PDFIn alignment with the global movement toward reducing animal testing, several reconstructed human epidermis (RHE) models have been created for conducting skin irritation tests. These models have undergone development, verification, validation, and integration into OECD TG 439. Our team has introduced a novel in-house RHE named GB-RHE, and we adhere to OECD TG 439 to pre-validate the model and test its potential employment for nanoparticle irritation studies.
View Article and Find Full Text PDFBiomed Rep
March 2025
Osteosarcoma (OS) is the most common malignant bone tumor affecting adolescents and young adults and it usually occurs in the long bones of the extremities. The detection of cancer-related genetic alterations has a growing effect in guiding diagnosis, prognosis and targeted therapies. However, little is known about the molecular aspects involved in the etiology and progression of OS, which limits options for targeted therapies.
View Article and Find Full Text PDFWater mint () is used in many formulations worldwide as a functional food and natural remedy to treat gastrointestinal disorders, lung diseases, and certain mental disorders such as epilepsy and depression. This study assessed the bioactivity of its infusion extract (INF) and hydroethanolic extract (HE) to highlight its health benefits. These extracts were analyzed for their chemical composition by HPLC-DAD-ESI-MSn, their antioxidant and antidiabetic properties, and their capacities to protect human erythrocytes against induced hemoglobin oxidation and lipid peroxidation.
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