Influence of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai on the growth of algae and wood decay fungi.

Polymeric alkylpyridinium salts (poly-APS) isolated from the marine sponge Reniera sarai act as antifouling and anticholinesterase agents. They also show moderate haemolytic and cytotoxic activities against different cell lines. The haemolytic activity of poly-APS is due to their detergent-like structure and behaviour in aqueous solutions.

Microcystins in Slovene freshwaters (central Europe)--first report.

Cyanobacterial blooms are frequent in the North-Eastern region of Slovenia, where the agricultural activities are intensive, resulting in higher water eutrophication. In a two year monitoring program we identified eighteen blooms of cyanobacteria, fifteen being hepatotoxic by intraperitoneal mouse bioassay. The approximate LD100 varied from 50-1000 mg/kg (dry cell weight/animal weight) and gross pathological signs were characteristic of cyanobacterial hepatotoxins.