Publications by authors named "G Koizumi"
Article Synopsis
- Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a condition affecting the jawbone and oral mucosa in patients treated with bisphosphonates.
- A study of a surgical specimen from a 61-year-old man revealed new histopathological findings, including pseudoepitheliomatous hyperplasia (PEH) and necrotic bone fragments in the oral mucosa.
- This research is significant as it is the first to report micro bone fragments associated with PEH in the oral mucosa of BRONJ patients.
Antiresorptive agent-related osteonecrosis of the jaw (ARONJ), a multifactorial disease, can drastically affect a patient’s quality of life. Moreover, disease progression to severe acute inflammation can hinder treatment. Therefore, we aimed to investigate the diagnostic value of the neutrophil−lymphocyte ratio (NLR) and platelet−lymphocyte ratio (PLR) in predicting the risk of acute inflammation in patients with ARONJ.
View Article and Find Full Text PDFChédiak-Higashi syndrome (CHS), a rare autosomal recessive disorder associated with leukocyte dysfunction, is characterised by partial skin and hair albinism, immunodeficiency, and abnormal bleeding. Furthermore, it may be associated with cognitive and neurological impairments. The long-term prognosis of patients is generally poor, and haematopoietic stem cell transplantation is a radical immunodeficiency treatment.
View Article and Find Full Text PDFThe aim of the study was to investigate the relationship between glucose effectiveness (Sg) and some metabolic parameters in male and female young Japanese. We measured plasma glucose and immunoreactive insulin levels in 1309 young Japanese persons (age <40 years) with normal glucose tolerance (NGT) before and at 30, 60, and 120 min during a 75 gram oral glucose tolerance test. We also measured serum adiponectin and high-sensitivity C-reactive protein (hsCRP) levels and oral glucose effectiveness (SgI), and investigated factors related to SgI.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers analyzed 29 OHCA patients, finding that high serum free T4 (F-T4) levels were positively correlated with ROSC, while low serum potassium and cortisol levels were also noteworthy in relation to patient outcomes.
- * The findings suggest that higher F-T4 levels may enhance heart cell responses and improve chances for ROSC, indicating a potential biomarker for prognosis in OHCA patients.