Occupational rhinitis in the Slovak Republic--a long-term retrospective study.

Background: Allergic and non-allergic rhinitis ranks among the common occupational health problems. However, data on the incidence of occupational rhinitis are lacking, since comprehensive studies are rare.

Methods: The study includes a group of patients in the Slovak Republic who were reported as having occupational rhinitis in the years 1990-2011.

Occupational dermatoses caused by contact with metalworking fluids in the region of central slovakia from 2000 to 2012.

Metalworking fluids (MWFs) are a common cause of allergic and irritant contact dermatitis. MWFs being currently used are mostly water based, containing biocides, emulsifiers, and other additives. We performed a retrospective analysis of the etiology of the occupational dermatoses caused by metalworking fluids in three regions of Central Slovakia (population of approximately 2 million) between 2000 and 2012.

Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes.

We evaluated chromosomal aberrations in lymphocytes of 177 workers exposed to xenobiotics in a tire plant and in 172 controls, in relation to their genetic background. Nine polymorphisms in genes encoding biotransformation enzymes and nine polymorphisms in genes involved in main DNA repair pathways were investigated for possible modulation of chromosomal damage. Chromosomal aberration frequencies were the highest among exposed smokers and the lowest in non-smoking unexposed individuals (2.

Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to cytostatics.

Objectives: Medical workers in oncological units have chronically been exposed to low doses of cytostatics (C) with potential consequences on DNA and chromosomal integrity. Our study addresses relationships between chromosomal aberrations (CAs), chromosome (CSA), and chromatid (CTA) types and polymorphisms in DNA repair genes XRCC1 and XRCC3.

Methods: The study was conducted on 72 exposed individuals from hospitals in Martin (HMT; 28 individuals), Ruzomberok (HRK; 31 medical workers) and in Trstená (HTS; 13 individuals), and on 34 unexposed individuals.

Health status of workers of a thermal power station exposed for prolonged periods to arsenic and other elements from fuel.

The Nováky Power Station (NPS) has been using since 1953 as fuel coal with a high content of As and with a low content of other metals. This involves a constant risk for the workers as well as pollution of the surroundings. The authors described 16 cases of chronic As intoxication in NPS workers after 22.