Brain tumor and achondroplasia: a case report and review of the literature.

This is the first reported case of a meningioma occurring in an achondroplastic dwarf. The patient had been treated for lumbar stenosis 7 years previously and later developed mental status change and visual loss due to a large tuberculum sella meningioma. Statistical analysis of the prevalence of both diseases in the United States shows insufficient evidence for a pathogenetic link between the two diseases.

Laminectomy: effects on postoperative technetium and gallium scintigraphy.

Bone scans using Tc-99m diphosphonate were found to become abnormal within 2 weeks after laminectomy in less than half of patients regardless of the extent of the operation. The degree of new uptake equaled that of the sacroiliac joints in only one of 19 patients with a normal preoperative scan. However, the Ga-67 citrate scan usually became abnormal (89%) postoperatively.

Penetration of nafcillin, methicillin, and cefazolin into human brain tissue.

To determine the penetration of the antistaphylococcal antibiotics, nafcillin, methicillin, and cefazolin, into brain tissue, we gave to each of 27 patients undergoing craniotomy and brain biopsy one of the antibiotics in a 2-g intravenous infusion just before operation. At the time of brain tissue removal (30 to 225 minutes after the start of the infusion), a serum specimen was obtained, and tissue and serum were assayed for antibiotic concentration. Eleven of 13 brain specimens contained detectable nafcillin concentrations between 0.

Short- and long-term results of microvascular anastomosis in the vertebrobasilar system, a critical analysis.

During the past five years, 22 patients were operated on and 21 occipital artery-caudal, loop-posterior, inferior cerebellar artery anastomoses were completed. All but one patient had suffered either TIAs of the vertebrobasilar system or brain stem stroke with complete or partial recovery. All the patients had significant atherosclerotic occlusive disease of both vertebral arteries and bilateral hypoplasia of the posterior communicating arteries.