[Morphologic manifestations of "prune belly" syndrome as shown by autopsy and surgical speciments].

The organs were morphologically studied in 21 children at the age of 4 days to 12 who died of or were operated for "prune belly" syndrome. Muscle hypoplasia and muscle aplasia in 2 cases in the anterior abdominal wall were found. Dysplastic processes with chronic pyelonephritis and ureteritis were observed in the kidneys and ureters.

[The effect of prenatal hyper- and hypoglycemia on liver mitochondrial function and carbohydrate metabolism in rat pups].

Hypoglycemia at the initial stage of the prenatal development decreased the level of glucose in the rat blood, increased glucose-6-phosphatase in the liver. Hyperglycemia increase the glucose content in the blood with relatively minor changes of the glucose-6-phosphatase activity and oxidation of hydrocarbonates.

[Effect of hyperglycemia and hyperthermia on liver mitochondrial respiration and blood glucose content of rats during postnatal ontogenesis].

Correlation between glucose level in blood and liver mitochondrial energetics of 1, 10, 20-days rats under hyperglycemia and high environmental temperature (38 degrees C) has been studied. Glucose feeding led to a significant increase of glucose content in blood, this increase being less at hyperthermia. Glucose feeding strengthened the oxidation of such intermediates as succinate (Krebs cycle), pyruvate and malate (hydrocarbonates) and caprylate (lipid).

[The effect of carbohydrate metabolic changes during pregnancy on the capacity of liver mitochondria in rat progeny to oxidize the lipid intermediate].

Respiration rate, respiration control and ADP of liver mitochondria were studies in one-, ten-, and twenty-day-old rats born of females who had received subcutaneous insulin injections (0.25 U/100 g body weight) on days 5-7, 11-13 and 19-21 of pregnancy or glucose (1 g/100 g body weight, in the morning before feeding). Caprylate, an intermediate of the lipid metabolism, was used as the substrate for oxidation.