Publications by authors named "G Kayser"

Background: In sub-Saharan Africa, rural areas have lower rates of access to safe drinking water compared to urban areas. We investigated predictors of Escherichia coli contamination in drinking water of rural households in Ghana, Malawi, Mozambique, Niger, Rwanda, Uganda, and Zambia.

Methods: We used a population-based, cluster randomized sampling design to select rural households in each country.

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Background: Organophosphate and pyrethroid insecticides can affect children's neurodevelopment and increase inflammation. Limited evidence exists among adolescents and on whether inflammation may mediate pesticide-neurobehavior associations. We examined the associations between insecticide metabolite concentrations and neurobehavior among adolescents in Ecuadorian agricultural communities.

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Article Synopsis
  • A study in Ecuador examined the effects of PFASs and pesticides on lung function in 381 adolescents, measuring their exposure to specific substances and assessing lung health over six years.
  • Individual substances like PFOA, glyphosate, and ethylene thiourea showed slight associations with lung function improvements, but most other exposures did not have significant effects.
  • Overall, the results suggest no strong evidence linking PFASs and pesticides with lung function changes in this population, especially after adjusting for various factors like household income and tobacco exposure.
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  • The study investigates low-grade salivary gland carcinoma treatment methods and the role of tumor budding as a prognostic factor, analyzing patient data from 2003 to 2017.
  • Results indicate that tumor budding does not significantly affect overall survival rates but correlates with disease-free survival, highlighting better outcomes for patients with low tumor budding.
  • The findings suggest tumor budding could serve as an important additional prognostic indicator, especially related to recurrence and nodal metastasis in low-grade salivary gland carcinomas.
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Carcinogenesis and tumor proliferation are characterized by a complex interaction of cancer cells with the tumor microenvironment. In particular, a tumor-promoting effect can be assumed for the stroma and its fibroblasts. An influence of the immune system on non small cell lung cancer (NSCLC) is now also suspected.

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