Publications by authors named "G Katsanos"
Detailed characterization of B cells in dialysis patients who are candidates for kidney transplant is still lacking, with little information on how dialysis duration and modality impact B cell subsets. Cluster analysis of flow cytometry determined the frequencies and absolute numbers of B-cell subsets and divided the cohort of 78 candidates into two distinct clusters, one with shorter and one with longer dialysis duration. The immune profiles of the clusters differed depending on whether frequencies or absolute counts were considered.
View Article and Find Full Text PDFRobotic median arcuate ligament release: a video vignette.
J Minim Invasive Surg
September 2024
Median arcuate ligament syndrome (MALS) poses a rare challenge in diagnosis and management. We present a case of MALS in a 50-year-old male with recurrent epigastric pain, vomiting, and diarrhea. Diagnostic imaging revealed celiac artery stenosis and gastroduodenal artery collateral dilatation.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to assess changes in immune cell counts in kidney transplant recipients over a year and how these changes relate to various clinical factors.
- - Using flow cytometry on 112 patients, researchers found most T cell subsets increase post-transplant, with variations influenced by recipient age, donor type, and dialysis method.
- - Key findings indicate that younger recipients and better graft function lead to higher T cell counts, while living donor kidneys and certain dialysis types positively affect immune recovery.
Article Synopsis
- The annual number of solid organ transplants is increasing, with kidneys, livers, and hearts being the most common, and outcomes are improving, leading to a higher likelihood that surgeons will manage transplant patients with acute abdominal issues.
- Complications in immunocompromised transplant patients can arise from both graft-related and non-graft-related problems, emphasizing the need for careful perioperative management, including immunosuppression regulation and cardiovascular evaluations.
- Atypical clinical presentations can delay diagnoses, increasing risks of morbidity and mortality, making early imaging, like multidetector CT scans, crucial for effective management in these patients.
Article Synopsis
- B and T regulatory cells (Bregs and Tregs) play a crucial role in kidney transplantation, and this study aims to track their changes in frequency and numbers before and after transplant.
- Researchers used flow cytometry to analyze cells from 50 kidney recipients without rejection, assessing renal function through estimated glomerular filtration rate (eGFR).
- Findings indicate that at six months post-transplant, Tregs, tBregs, and plasmablasts decreased in frequency, whereas mBregs remained stable; notably, better graft function correlates positively with tBregs and plasmablasts, especially when eGFR is above 60.