Prevention of complications related to traumatic brain injury in children and adolescents with creatine administration: an open label randomized pilot study.

Background: There has been an enormous focus on the discovery and development of neuroprotective agents that might have clinical relevance after traumatic brain injury (TBI). Based on experimental facts, we studied administration of creatine to patients with TBI.

Methods: A prospective, randomized, comparative, open-labeled pilot study of the possible neuroprotective effect of creatine was performed on 39 children and adolescents, aged between 1 to 18 years old, with TBI.

Psychosis-like syndrome associated with intermittent intracranial hypertension caused by a large arachnoid cyst of the left temporal lobe.

Lesions on certain brain areas can cause psychiatric signs. Symptomatic arachnoid cysts can produce a variety of symptoms like headache, seizures, increased ICP, and rarely psychiatric disorders. We report a case of a young woman with a left temporal lobe arachnoid cyst, presented with headache and an atypical psychosis.

Use of polytetrafluoroethylene dural substitute as adhesion preventive material during craniectomies.

Objective: We describe the use of an artificial dural substitute in order to prevent peridural fibrosis in patients who underwent craniectomy and subsequent cranioplasty.

Patients And Methods: In our institution we performed decompressive craniectomy and subsequent cranioplasty, with autologous bone flap, in 52 patients (mean age 32 years) between 1998 and 2004. Most of the craniectomy procedures were performed as emergency, brain swelling relief, measure for various reasons.