Publications by authors named "G Kahlmeter"
Background And Objective: Infection after transrectal prostate biopsy (TPBx) is a well-known risk. A comprehensive investigation of risk factors may identify measures for safe TPBx as an alternative to a change in biopsy route. The aim of this study was to identify risk factors for infection after TPBx.
View Article and Find Full Text PDFPrimary care antimicrobial stewardship programs have limited success in reducing antibiotic use, prompting the search for new strategies. Convincing general practitioners to resist antibiotic prescription amid uncertainty or patient demands usually poses a significant challenge. Despite common practice, standard durations for common infections lack support from clinical studies.
View Article and Find Full Text PDFAntimicrobial resistance in uropathogens commonly causing urinary tract infections (UTIs) is a growing problem internationally. Pivmecillinam, the oral prodrug of mecillinam, has been used for over 40 years, primarily in Northern Europe and Canada. It is recommended in several countries as a first-line agent for the treatment of uncomplicated UTIs (uUTIs) and is now approved in the United States.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to establish standardized methods for antimicrobial susceptibility testing of Bacillus anthracis across Europe, addressing the absence of clinical breakpoints from EUCAST.
- About 335 B. anthracis isolates were tested using two methodologies, revealing wild-type distributions and defined epidemiological cut-off values (ECOFFs) for ten key antimicrobials.
- Results showed resistance in some strains, with implications for monitoring resistance development and the need for further genetic investigations on isolates exhibiting slightly increased minimum inhibitory concentrations (MICs).
Background: Evidence-based clinical susceptibility breakpoints have been lacking for antimicrobial agents used for diphtheria.
Objectives: We aimed to evaluate broth microdilution and disc diffusion methods and create a dataset of MIC values and inhibition zone diameters (ZDs) from which breakpoints could be determined.
Methods: We included 400 recent clinical isolates equally distributed by species (Corynebacterium diphtheriae and Corynebacterium ulcerans) and by national surveillance programmes (France and Germany).