Comparative study of phenotypic and genotypic expression of virulence factors in colonizing and pathogenic carbapenem resistant Acinetobacter baumannii (CRAB).

Carbapenem resistant Acinetobacter baumannii has evolved as the most troublesome microorganism with multiple virulence factors. Biofilm formation, porins, micronutrient capturing mechanism and quorum sensing, provide protection against desiccation, host-pathogen killing and enhance its persistence. The conservation of these factors between colonizing and pathogenic carbapenem resistant A.

Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.

Cyclic nucleotide GMP-AMP (cGAMP) plays a critical role in mediating the innate immune response through the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway. Recent studies showed that ATP-binding cassette subfamily C member 1 (ABCC1) is a cGAMP exporter. The exported cGAMP can be imported into uninfected cells to stimulate a STING-mediated innate immune response.

Molecular requirements of chromogranin B for the long-sought anion shunter of regulated secretion.

Unlabelled: All eukaryotes utilize regulated secretion to release molecular signals packaged in secretory granules for local and remote signaling. An anion shunt conductance was first suggested in secretory granules of bovine chromaffin cells nearly five decades ago. Biochemical identity of this conductance remains undefined.

Energy Transfer Studies on Red Emitting CaGdSbWO: Sm/Eu Phosphor for w-LEDs and Indoor Plant Growth Lighting System.

In the present research work, a solid-state reaction method was employed to synthesize a series of CaGdSbWO:SmEu (x = 1, 1.5, 2, 3 and 4 mol%) phosphors. The phase purity, crystallinity, morphological and compositional studies were analysed via X-ray diffraction (XRD), scanning electron microscopy (SEM) imaging, and energy dispersive spectroscopy (EDS) analysis.