[Thermal skin reaction to food intake and its changes in certain forms of obesity].

The authors review data on recently discovered temperature response of deep skin layers to the meal. The reaction is of a reflex nature and is one of the mechanisms regulating heat exchange in the body. In healthy people this reaction is weak.

[Thermal reaction of subcutaneous tissue to food intake in patients with obesity].

Investigating the temperature of deep layers of skin and in the main of subcutaneous tissue in patients with obesity we found the close connection between changes of this temperature and food intake. In patients who are in postabsorptive period the intake of the small portion of test food (220 kcal) induces in 3-4 min a marked increase of the subcutaneous tissue temperature (often by 1.0-1.

[Effect of glutamate and combined with inosine monophosphate on gastric secretion].

Experiments on dogs with Pavlov pouch and gastric fistula demonstrate that monosodium glutamate (MSG) enriched with inosine monophosphate (IMP) potentiate pentagastrin-induced gastric secretion. The preparation (Chi-Mi) was introduced directly into the intestine through a fistula. When given alone in an equal quantity MSG produced the same effect.

[Reflex of food-induced thermogenesis in normal subjects and its changes in patients with obesity].

Dog experiments have established that an initial period of food-induced thermogenesis (FIT) has a reflex nature. This is proved by FIT appearance in sham feeding and disappearance after atropine administration. Various food substances proved capable of evoking this reflex.

[The use of monosodium glutamate in the combined therapy of patients with atrophic gastritis].

Monosodium glutamate (MSG) taken per os has been found to stimulate gastric secretion provoked by pentagastrin. MSG gave rise to a marked elevation of endogenic gastrin levels both in experimental animals and atrophic gastritis patients. Thirty-six patients with secretory gastric insufficiency received MSG as an additive to their food during combined therapy of their disease.