Publications by authors named "G K Chew"

Proliferative Vitreoretinopathy (PVR) is a major complication of surgical repair for Rhegmatogenous Retinal Detachment (RRD). Methotrexate (MTX), a folate antimetabolite, has shown promise in targeting the pathological processes involved in PVR, such as cell proliferation inhibition, fibrosis and anti-inflammation. Systematic review examines the use of MTX in PVR by analysing different administration methods and outcomes.

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Introduction: The avoidance of asthma triggers, like tobacco smoke, facilitates asthma management. Reliance upon caregiver report of their child's environmental tobacco smoke (ETS) exposure may result in information bias and impaired asthma management. This analysis aimed to characterize the chronicity of ETS exposure, assess the validity of caregiver report of ETS exposure, and investigate the relationship between ETS exposure and asthma attack.

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Article Synopsis
  • Hurricane Ida, a Category 4 hurricane, struck southern Louisiana in August 2021, resulting in significant wind damage and flooding, prompting an investigation into mold exposure and cleanup practices in the affected areas.
  • The study focused on assessing the knowledge, attitudes, and practices related to mold among 238 residents and 68 mold-remediation workers, comparing findings to data from the aftermath of Hurricane Katrina 16 years prior.
  • While awareness of safety measures improved since Hurricane Katrina, actual adherence to those measures remained low, with many participants using inadequate personal protective equipment despite understanding the health risks associated with mold exposure.
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Background: Transcriptomic changes in the essential tremor (ET)-associated cerebello-thalamo-cortical "tremor network" and their association to brain structure have not been investigated.

Objective: The aim was to characterize molecular changes associated with network-level imaging-derived phenotypes (IDP) found in ET.

Methods: We performed an imaging-transcriptomic study in British adults using imaging-genome-wide association study summary statistics (UK Biobank "BIG40" cohort; n = 33,224, aged 40-69 years).

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