Superconducting transition-edge sensors (TES) have emerged as fascinating devices to detect broadband electromagnetic radiation with low thermal noise. The advent of metallic transition metal dichalcogenides, such as NbSe, has also created an impetus to understand their low-temperature properties, including superconductivity. Interestingly, NbSe-based sensor within the TES framework remains unexplored.
View Article and Find Full Text PDFResearch suggests that how people feel about aging can contribute to their later physical, cognitive, and mental health. In two studies, we examined younger (ages 18-30) and older adults' (ages 61-70) views about aging by asking them to rate the extent to which they would find it desirable to be various ages between 0 and 120. Participants also indicated both their ideal age (the age at which they would most like to be) and their subjective age (how old they generally feel).
View Article and Find Full Text PDFRecently, there has been increased interest in using mannan as an immunomodulatory bioconjugate. Despite notable immunological and functional differences between the reduced (R-Man) and oxidized (O-Man) forms of mannan, little is known about the impact of mannan oxidation state on its persistence or its potential controlled release from biomaterials that may improve immunotherapeutic or prophylactic efficacy. Here, we investigate the impact of oxidation state on the and release of mannan from a biocompatible and immunostimulatory multidomain peptide hydrogel, K(SL)K (abbreviated as K), that has been previously used for the controlled release of protein and small molecule payloads.
View Article and Find Full Text PDFAdjuvants play a critical role in enhancing vaccine efficacy; however, there is a need to develop new immunomodulatory compounds to address emerging pathogens and to expand the use of immunotherapies. Multidomain peptides (MDPs) are materials composed of canonical amino acids that form injectable supramolecular hydrogels under physiological salt and pH conditions. MDP hydrogels are rapidly infiltrated by immune cells and have previously been shown to influence cytokine production.
View Article and Find Full Text PDFThe hybrid structure of zero-dimensional (0D) graphene quantum dots (GQDs) and semiconducting two-dimensional (2D) MoS has been investigated, which exhibit outstanding properties for optoelectronic devices surpassing the limitations of MoS photodetectors where the GQDs extend the optical absorption into the near-UV regime. The GQDs and MoS films are characterized by Raman and photoluminescence (PL) spectroscopies, along with atomic force microscopy. After outlining the fabrication of our 0D-2D heterostructure photodetectors comprising GQDs with bulk MoS sheets, their photoresponse to the incoming radiation was measured.
View Article and Find Full Text PDF